Hepatic and splenic uptake of Tc-99m HDP in multiple myeloma: additional findings on Tc-99m MIBI and Tc-99m sulfur colloid images.

Multiple myeloma in a patient with suspected hyperparathyroidism

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of terminally differentiated plasma cells. Imaging modalities which allow the recognition of the effects of myeloma cells on the skeletal system have been utilized for a long time. Herein, we represent a patient with generalized osteoporosis and hypercalcemia, who was referred for parathyroid scan, in whom the widespread bone marrow techne...

Massive hepatomegaly in 99mTc-octreotide scintigraphy: The value of 99mTc-sulfur colloid scan

99mTc-octreotide scintigraphy, performed during the following up a 58-year old man with neuroendocrine tumor demonstrated massive hepatomegaly demonstrating multiple areas of increased and decreased uptake. Due to severe hepatomegaly concurrence of any other abdominal soft tissue lesions could not be excluded. A 99mTc-sulfur colloid scan was done and thoroughly compared wi...

Technetium 99m sestamibi in multiple myeloma.

bone involvement. Destruction is mediated through normal osteoclasts, which respond to local osteoclast-activating microenvironment [7]. Technetium-99m 2methoxyisobutylisonitrile (TC-99m MIBI) is a lipophilic agent that accumulates within living malignant cells due to the higher transmembrane electrical potential as a consequence of the higher metabolic rate than in the surrounding normal cells...

The value of Tc-99m MIBI scintigraphy in active diseases and remission phase of multiple myeloma [Persian]

Multiple brown tumors in a patient with parathyroid adenoma depicting affinity for both 99mTc -pertechnetate and 99mTc-MIBI: Evaluation with hybrid SPECT/CT

 Parathyroid adenoma involving a single parathyroid gland is the underlying cause of 80-85% of primary hyperparathyroidism (PHPT). Skeletal system is significantly affected by PHPT. Brown tumors are known to have affinity for 99mTc-MIBI. We report a rare case of PHPT presenting with diffuse bony pain, high calcium level and significantly elevated alkaline phosphatase level. 99m<...